CNBC.com's News Now

Thursday, Feb. 21, 2008

1. Boone Pickens on $100 Oil: Boone Pickens, BP Capital CEO, sheds light on where oil is going. 2. Microsoft Making "Strategic" Changes: A look at what it means for the software giant, with Brendan Barnicle, Pacific Crest Securities sr. research analyst and CNBC's Melissa Francis. 3. More Write-Downs Ahead? The Citigroup research of Meredith Whitney, executive director of CIBC World Markets, triggered a staggering global selloff. Now she's warning banks could face additional write-downs of up to $70B if bond insurers are downgraded. 4. Wall Street Layoffs Looming: A new round of cost cutting may soon hit Wall Street as financial firms look to offset write-downs, reports CNBC's Charlie Gasparino. 5. Sugar vs Splenda: A bittersweet battle, with CNBC's Jane Wells. Genentech's Avastin: Will FDA Give It An "Oscar"? A big day tomorrow for Genentech's Avastin. The FDA is scheduled to rule on whether it can be used for breast cancer treatment. Mike Huckman blogs on what the ruling means for cancer patients and Genentech's shareholders. Click here to view posting.

PHARMA IN COURT: The U.S. Supreme Court is scheduled to hear a case on Monday that could save the pharmaceutical industry billions in consumer lawsuits. A diabetes drug was removed from the market in 2000 and the court will decide whether or not plaintiffs can sue in state court for adverse effects when a drug has received FDA approval. Hampton Pearson is on the sidelines previewing the possibilities for business if the Supreme Court swings in the favor of big pharma. STAKES ARE BIGGER IN TEXAS: While Barack Obama's momentum continues to sweep through the primaries, Hillary Clinton continues to fight for revival. John Harwood details the triumphs and travails from Thursday night's Democratic debate. Who won the war of words in the lone star debate? DIGESTING FAST FOOD STRATEGIES: Friday morning, Burger King will unveil five new burgers on Squawk Box. With mixed business strategies in this period of possible stagflation, Phil LeBeau chews on the state of the fast food industry. FROM NAUGHT TO HOT: Every year, the same two Price Waterhouse Coopers accountants walk the red carpet with the key to the night handcuffed to their wrist. They tally the ballots and deliver the results to the stage. The academy has relied on PWC for decades, and it's been the same two guys working around the clock, every year. Julia Boorstin goes behind the scenes with PWC to see how the ballot process works. Who knew accountants could have such an enviable job? SUBS FOR SALE: Forget Bentleys, mansions or yachts, the latest toy for the uber-wealthy is to own one's own submersible. Paul Allen reportedly bought his "yellow submarine" for $12 million. Jane Wells goes to the most cutting-edge personal submarine company, revealing for the first time, the submarine it was building for adventurer Steve Fossett...but now looking for a new buyer. They're currently working on another sub for venture capitalist guru Tom Perkins. Portfolio Watchlist Insider Trends Financial Glossary Stock Screeners Fund Screeners Earnings Screeners

To unsubscribe to this email click here If this e-mail was forwarded to you and you would like to subscribe to CNBC.com's News Now mailing, please click here